Excerpt from Page 19 – “Neurochemistry basics”

Published August 15, 2016

HOOKED: A concise guide to the underlying mechanics of addiction and treatment for patients, families, and providers | Arwen Podesta, MD

Excerpt from Page 19 – “Neurochemistry basics”

Everyone has different brain chemistry. We need to get into the
neurochemistry to deeper understand addiction and drug use. The
neurotransmitters, or brain chemical signals, of interest are
dopamine, serotonin, GABA, glutamate, and enkephalins.
Dopamine is the alarm, causing wakefulness, focus, reward, and
pleasure. Serotonin is related to mood, memory, mental well-being,
cognition, and sleep. GABA and glutamate are opposites, working
to balance each other with GABA calming and dampening anxiety
and glutamate causing excitation. Enkephalins are the brains natural
opioids, which give pleasure and reward, kill pain, and more.